Understanding Disorders: Insights into Phenotypes, Endophenotypes, Neurotypes, and Genotypes within the Context of the PENG Model

Kok Hwee CHIA

doi:10.64663/aet.53

Authors

Kok Hwee CHIA Merlion Paediatric Therapy Clinic, Singapore https://orcid.org/0000-0002-3645-2602

DOI:

https://doi.org/10.64663/aet.53

Keywords:

Endophenotypes, Genotypes, Neurotypes, PENG model, Phenotypes

Abstract

Advancements in neuroscience, genetics, and psychology have paved the way for a deeper understanding of human disorders and syndromes through the study of Phenotypes, Endophenotypes, Neurotypes, and Genotypes, collectively known as the PENG model. The framework of PENG provides critical insights into the complex interplay between biological, neurological, and behavioral factors, allowing for a more comprehensive understanding of individual and group differences. This approach enhances precision in diagnostics and fosters personalized treatment interventions, ultimately contributing to better clinical outcomes. As research continues to uncover these connections, it supports a shift towards more inclusive and compassionate approaches to mental health and neurodiversity, promising new pathways for individualized care and societal acceptance.

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